Microbiology Wageningen, 6700 AA (Gelderland), 38 hours per week
Job description
------------------------------
Systems Biology is a rapidly developing scientific discipline that aims at
explaining, predicting and controlling the complex cellular and
physiological phenomena of living organisms in terms of the underlying
chemical and physical processes and the involved feedback regulations. The
current project aims to investigate the metabolism of the thermophilic
bacterium Caldicellulosiruptor saccharolyticus, which is known for its high
capacity to produce hydrogen. According to various recent reports, hydrogen
will be an important renewable energy carrier in the future. For
thermodynamic reasons, hydrogen production is more feasible at elevated
temperatures and fermentation studies have shown that C. saccharolyticus can
indeed produce relatively high amounts of H2. The complete genome sequence
was analysed recently and a DNA micro-array system has been established. The
focus of the project will be on the main pathways leading to hydrogen, and
quantitative data on key enzymes and metabolites need to be determined.
Caldicellulosiruptor saccharolyticus will be cultured under defined
conditions (chemostat) and the physiological, biochemical and genetic
response will be analyzed by different techniques (transcriptomics,
metabolomics, and biochemistry). The data obtained will be used to
mathematically model the various interactions at the cellular level. This
project will be carried out in close collaboration with an ongoing
biohydrogen project.
Requirements
------------------------------
Required education/skills:University Graduate
Recently obtained Masters degree in Biology, Molecular Sciences, or
Biotechnology. Basic knowledge of microbial genetics and/or physiology.
Practical experience with anaerobic culturing and analytical techniques such
as HPLC, GC and MS techniques is desirable. Affinity with mathematical
modelling is considered an advantage. Good communication skills (written,
oral) in English.
Job type: Research / Advising
Workfield(s):
- Research trainees, non-tenured lecturers, researchers(Scientific
discipline: Natural Sciences)
Organization
------------------------------
Agrotechnology & Food Sciences Group
Laboratory of Microbiology
AFSG is the organisation for development and transfer of knowledge in the
field of sustainable applications of agro-components for safe and healthy
food and non-food products.
Conditions of employment
------------------------------
Estimated maximum salary per month: eur 2500 - 3000
Salary: scale 10.
Maximum salary amount in Euro's a month 2502
Employment basis: Temporary for specified period
Duration of the contract: 1 3 years
Maximum hours per week: 38
Additional conditions of employment:
The PhD will be appointed for a fulltime position for 4 years at the
Laboratory of Microbiology at Wageningen University. Gross maximum salary
per month € 1956 in the first year, growing to €2502 in the last year based
on full-time employment.
Hay-profile: AIO (PhD student).
You will be member of a multidisciplinary research group of senior
scientists, post-docs, and PhD students and you will have access to state-of
the art facilities and equipment.
Additional Information
------------------------------
Additional information about the vacancy can be obtained from:
Dr. Servé Kengen
Telephone number: 0317 483737
E-mail address: serve.kengen@wur.nl
Application
------------------------------
You can apply for this job before 29-12-2007 (dd-mm-yyyy) by sending your
application to:
Wageningen UR - AFSG
bode 118
K. den Ridder
P.O. Box 17
6700 PD Wageningen
Netherlands
E-mail: afsg-vacatures@wur.nl<afsg-vacatures@wur.nl?subject=Application%20PhDSystems%20Biology>
When applying for this job always mention the vacancynumber AFSG 07.155.
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